diff --git a/bolt/CMakeLists.txt b/bolt/CMakeLists.txt
index 5c7d51e1e398..9158552fa09b 100644
--- a/bolt/CMakeLists.txt
+++ b/bolt/CMakeLists.txt
@@ -55,9 +55,9 @@ if(BOLT_BUILT_STANDALONE)
   include_directories(${LLVM_INCLUDE_DIRS})
   link_directories("${LLVM_LIBRARY_DIR}")
 
-  set( CMAKE_RUNTIME_OUTPUT_DIRECTORY "${CMAKE_INSTALL_BINDIR}" )
-  set( CMAKE_LIBRARY_OUTPUT_DIRECTORY "${CMAKE_INSTALL_LIBDIR}/${LLVM_LIBDIR_SUFFIX}" )
-  set( CMAKE_ARCHIVE_OUTPUT_DIRECTORY "${CMAKE_INSTALL_LIBDIR}/${LLVM_LIBDIR_SUFFIX}")
+  set( CMAKE_RUNTIME_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/bin" )
+  set( CMAKE_LIBRARY_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/lib${LLVM_LIBDIR_SUFFIX}" )
+  set( CMAKE_ARCHIVE_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/lib${LLVM_LIBDIR_SUFFIX}")
 endif() # standalone
 
 # Determine default set of targets to build -- the intersection of
diff --git a/bolt/runtime/CMakeLists.txt b/bolt/runtime/CMakeLists.txt
index 63f178bd263c..55c582313e47 100644
--- a/bolt/runtime/CMakeLists.txt
+++ b/bolt/runtime/CMakeLists.txt
@@ -64,8 +64,8 @@ target_include_directories(bolt_rt_instr PRIVATE ${CMAKE_CURRENT_BINARY_DIR})
 target_compile_options(bolt_rt_hugify PRIVATE ${BOLT_RT_FLAGS})
 target_include_directories(bolt_rt_hugify PRIVATE ${CMAKE_CURRENT_BINARY_DIR})
 
-install(TARGETS bolt_rt_instr DESTINATION "lib${LLVM_LIBDIR_SUFFIX}")
-install(TARGETS bolt_rt_hugify DESTINATION "lib${LLVM_LIBDIR_SUFFIX}")
+install(TARGETS bolt_rt_instr DESTINATION ${CMAKE_INSTALL_LIBDIR})
+install(TARGETS bolt_rt_hugify DESTINATION ${CMAKE_INSTALL_LIBDIR})
 
 if (CMAKE_CXX_COMPILER_ID MATCHES ".*Clang.*" AND CMAKE_SYSTEM_NAME STREQUAL "Darwin")
   add_library(bolt_rt_instr_osx STATIC
@@ -77,7 +77,7 @@ if (CMAKE_CXX_COMPILER_ID MATCHES ".*Clang.*" AND CMAKE_SYSTEM_NAME STREQUAL "Da
   target_compile_options(bolt_rt_instr_osx PRIVATE
     -target x86_64-apple-darwin19.6.0
     ${BOLT_RT_FLAGS})
-  install(TARGETS bolt_rt_instr_osx DESTINATION "lib${LLVM_LIBDIR_SUFFIX}")
+  install(TARGETS bolt_rt_instr_osx DESTINATION ${CMAKE_INSTALL_LIBDIR})
 
   if(NOT BOLT_BUILT_STANDALONE)
     add_custom_command(TARGET bolt_rt_instr_osx POST_BUILD
diff --git a/clang/cmake/caches/CrossWinToARMLinux.cmake b/clang/cmake/caches/CrossWinToARMLinux.cmake
index c47c4ac3bb73..721eb2cfd302 100644
--- a/clang/cmake/caches/CrossWinToARMLinux.cmake
+++ b/clang/cmake/caches/CrossWinToARMLinux.cmake
@@ -152,7 +152,7 @@ endif()
 # Set up RPATH for the target runtime/builtin libraries.
 # See some details here: https://reviews.llvm.org/D91099
 if (NOT DEFINED RUNTIMES_INSTALL_RPATH)
-  set(RUNTIMES_INSTALL_RPATH                "\$ORIGIN/../lib;${CMAKE_INSTALL_PREFIX}/lib")
+  set(RUNTIMES_INSTALL_RPATH                "\$ORIGIN/../lib;${CMAKE_INSTALL_FULL_LIBDIR}")
 endif()
 
 set(LLVM_BUILTIN_TARGETS                    "${TOOLCHAIN_TARGET_TRIPLE}" CACHE STRING "")
diff --git a/clang/cmake/modules/AddClang.cmake b/clang/cmake/modules/AddClang.cmake
index 4059fc3e986c..2b2500ad655c 100644
--- a/clang/cmake/modules/AddClang.cmake
+++ b/clang/cmake/modules/AddClang.cmake
@@ -134,8 +134,8 @@ macro(add_clang_library name)
         install(TARGETS ${lib}
           COMPONENT ${lib}
           ${export_to_clangtargets}
-          LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX}
-          ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX}
+          LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR}
+          ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR}
           RUNTIME DESTINATION "${CMAKE_INSTALL_BINDIR}")
 
         if (NOT LLVM_ENABLE_IDE)
diff --git a/clang/tools/scan-build-py/CMakeLists.txt b/clang/tools/scan-build-py/CMakeLists.txt
index 84087a9fd8d2..2d9bb08c5438 100644
--- a/clang/tools/scan-build-py/CMakeLists.txt
+++ b/clang/tools/scan-build-py/CMakeLists.txt
@@ -91,7 +91,7 @@ if(CLANG_INSTALL_SCANBUILDPY)
                        DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/lib/libscanbuild/${lib})
     list(APPEND Depends ${CMAKE_BINARY_DIR}/lib/libscanbuild/${lib})
     install(FILES lib/libscanbuild/${lib}
-            DESTINATION lib/libscanbuild
+            DESTINATION ${CMAKE_INSTALL_LIBDIR}/libscanbuild
             COMPONENT scan-build-py)
   endforeach()
 
@@ -109,7 +109,7 @@ if(CLANG_INSTALL_SCANBUILDPY)
                        DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/lib/libscanbuild/resources/${resource})
     list(APPEND Depends ${CMAKE_BINARY_DIR}/lib/libscanbuild/resources/${resource})
     install(FILES lib/libscanbuild/resources/${resource}
-            DESTINATION lib/libscanbuild/resources
+            DESTINATION ${CMAKE_INSTALL_LIBDIR}/libscanbuild/resources
             COMPONENT scan-build-py)
   endforeach()
 
@@ -125,7 +125,7 @@ if(CLANG_INSTALL_SCANBUILDPY)
                        DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/lib/libear/${lib})
     list(APPEND Depends ${CMAKE_BINARY_DIR}/lib/libear/${lib})
     install(FILES lib/libear/${lib}
-            DESTINATION lib/libear
+            DESTINATION ${CMAKE_INSTALL_LIBDIR}/libear
             COMPONENT scan-build-py)
   endforeach()
 
diff --git a/cmake/Modules/GNUInstallPackageDir.cmake b/cmake/Modules/GNUInstallPackageDir.cmake
index e4a058e68f4f..e4e84b6fc057 100644
--- a/cmake/Modules/GNUInstallPackageDir.cmake
+++ b/cmake/Modules/GNUInstallPackageDir.cmake
@@ -29,5 +29,5 @@ macro(_GNUInstallPackageDir_cache_path var default description)
   _GNUInstallPackageDir_cache_convert_to_path("${var}" "${description}")
 endmacro()
 
-_GNUInstallPackageDir_cache_path(CMAKE_INSTALL_PACKAGEDIR "lib${LLVM_LIBDIR_SUFFIX}/cmake"
+_GNUInstallPackageDir_cache_path(CMAKE_INSTALL_PACKAGEDIR "${CMAKE_INSTALL_LIBDIR}/cmake"
   "Directories containing installed CMake modules (lib/cmake)")
diff --git a/cmake/Modules/GetClangResourceDir.cmake b/cmake/Modules/GetClangResourceDir.cmake
index 518220188f96..d8b046fdca4c 100644
--- a/cmake/Modules/GetClangResourceDir.cmake
+++ b/cmake/Modules/GetClangResourceDir.cmake
@@ -16,7 +16,7 @@ function(get_clang_resource_dir out_var)
     if (NOT CLANG_VERSION_MAJOR)
       string(REGEX MATCH "^[0-9]+" CLANG_VERSION_MAJOR ${PACKAGE_VERSION})
     endif()
-    set(ret_dir lib${LLVM_LIBDIR_SUFFIX}/clang/${CLANG_VERSION_MAJOR})
+    set(ret_dir ${CMAKE_INSTALL_LIBDIR}/clang/${CLANG_VERSION_MAJOR})
   endif()
 
   if(ARG_PREFIX)
diff --git a/compiler-rt/cmake/Modules/CompilerRTAIXUtils.cmake b/compiler-rt/cmake/Modules/CompilerRTAIXUtils.cmake
index 20400014869e..a4fe2fafe616 100644
--- a/compiler-rt/cmake/Modules/CompilerRTAIXUtils.cmake
+++ b/compiler-rt/cmake/Modules/CompilerRTAIXUtils.cmake
@@ -53,7 +53,7 @@ macro(archive_aix_libatomic name libname)
     # setting _install_rpath on AIX for reference.
     if(LLVM_LIBRARY_OUTPUT_INTDIR AND CMAKE_INSTALL_PREFIX)
       set(output_dir "${LLVM_LIBRARY_OUTPUT_INTDIR}")
-      set(install_dir "${CMAKE_INSTALL_PREFIX}/lib${LLVM_LIBDIR_SUFFIX}")
+      set(install_dir "${CMAKE_INSTALL_FULL_LIBDIR}")
     else()
       get_compiler_rt_output_dir(${COMPILER_RT_DEFAULT_TARGET_ARCH} output_dir)
       get_compiler_rt_install_dir(${COMPILER_RT_DEFAULT_TARGET_ARCH} install_dir)
diff --git a/flang/cmake/modules/AddFlang.cmake b/flang/cmake/modules/AddFlang.cmake
index ca233103ccdb..3e4dd9a58c5f 100644
--- a/flang/cmake/modules/AddFlang.cmake
+++ b/flang/cmake/modules/AddFlang.cmake
@@ -81,8 +81,8 @@ function(add_flang_library name)
       install(TARGETS ${name}
         COMPONENT ${name}
         ${export_to_flangtargets}
-        LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX}
-        ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX}
+        LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR}
+        ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR}
         RUNTIME DESTINATION "${CMAKE_INSTALL_BINDIR}")
 
       if (NOT LLVM_ENABLE_IDE)
diff --git a/libclc/libclc.pc.in b/libclc/libclc.pc.in
index 3a9e58b3ef0c..60f8c0fdf75d 100644
--- a/libclc/libclc.pc.in
+++ b/libclc/libclc.pc.in
@@ -1,4 +1,4 @@
-libexecdir=@CMAKE_INSTALL_PREFIX@/@CMAKE_INSTALL_DATADIR@/clc
+libexecdir=@CMAKE_INSTALL_FULL_DATAROOTDIR@/clc
 
 Name: libclc
 Description: Library requirements of the OpenCL C programming language
diff --git a/libcxx/test/configs/armv7m-picolibc-libc++.cfg.in b/libcxx/test/configs/armv7m-picolibc-libc++.cfg.in
index f0782c28ce3e..32fc542db557 100644
--- a/libcxx/test/configs/armv7m-picolibc-libc++.cfg.in
+++ b/libcxx/test/configs/armv7m-picolibc-libc++.cfg.in
@@ -1,6 +1,6 @@
 lit_config.load_config(config, '@CMAKE_CURRENT_BINARY_DIR@/cmake-bridge.cfg')
 
-libc_linker_script = '@CMAKE_INSTALL_PREFIX@/lib/picolibcpp.ld'
+libc_linker_script = '@CMAKE_INSTALL_FULL_LIBDIR@/picolibcpp.ld'
 
 config.substitutions.append(('%{flags}', '--sysroot=@CMAKE_INSTALL_PREFIX@'))
 
diff --git a/libcxxabi/test/configs/armv7m-picolibc-libc++abi.cfg.in b/libcxxabi/test/configs/armv7m-picolibc-libc++abi.cfg.in
index e61efbb303fc..a73c58584567 100644
--- a/libcxxabi/test/configs/armv7m-picolibc-libc++abi.cfg.in
+++ b/libcxxabi/test/configs/armv7m-picolibc-libc++abi.cfg.in
@@ -1,6 +1,6 @@
 lit_config.load_config(config, '@CMAKE_CURRENT_BINARY_DIR@/cmake-bridge.cfg')
 
-libc_linker_script = '@CMAKE_INSTALL_PREFIX@/lib/picolibcpp.ld'
+libc_linker_script = '@CMAKE_INSTALL_FULL_LIBDIR@/picolibcpp.ld'
 
 config.substitutions.append(('%{flags}', '--sysroot=@CMAKE_INSTALL_PREFIX@'))
 
diff --git a/libdevice/cmake/modules/SYCLLibdevice.cmake b/libdevice/cmake/modules/SYCLLibdevice.cmake
index 4f7d06e668ba..7ecd77ebc002 100644
--- a/libdevice/cmake/modules/SYCLLibdevice.cmake
+++ b/libdevice/cmake/modules/SYCLLibdevice.cmake
@@ -6,15 +6,15 @@ else()
   set(devicelib_host_static_obj libsycl-devicelib-host.a)
 endif()
 set(bc-suffix bc)
-set(install_dest_obj lib${LLVM_LIBDIR_SUFFIX})
+set(install_dest_obj ${CMAKE_INSTALL_LIBDIR})
 
 if(WIN32)
   # On Windows, install to lib/
-  set(install_dest_bc lib${LLVM_LIBDIR_SUFFIX})
+  set(install_dest_bc ${CMAKE_INSTALL_LIBDIR})
   set(bc_binary_dir "${CMAKE_LIBRARY_OUTPUT_DIRECTORY}")
 else()
   # On other platforms, install to lib/dpcpp-<major_ver>/sycl
-  set(bc_dir "lib${LLVM_LIBDIR_SUFFIX}/dpcpp-${DPCPP_VERSION_MAJOR}/sycl")
+  set(bc_dir "${CMAKE_INSTALL_LIBDIR}/dpcpp-${DPCPP_VERSION_MAJOR}/sycl")
   set(install_dest_bc ${bc_dir})
   set(bc_binary_dir "${CMAKE_BINARY_DIR}/${bc_dir}")
 endif()
diff --git a/libunwind/test/configs/armv7m-picolibc-libunwind.cfg.in b/libunwind/test/configs/armv7m-picolibc-libunwind.cfg.in
index 6ffdd70c6177..fadb6b3cb02f 100644
--- a/libunwind/test/configs/armv7m-picolibc-libunwind.cfg.in
+++ b/libunwind/test/configs/armv7m-picolibc-libunwind.cfg.in
@@ -1,6 +1,6 @@
 lit_config.load_config(config, '@CMAKE_CURRENT_BINARY_DIR@/cmake-bridge.cfg')
 
-libc_linker_script = '@CMAKE_INSTALL_PREFIX@/lib/picolibcpp.ld'
+libc_linker_script = '@CMAKE_INSTALL_FULL_LIBDIR@/picolibcpp.ld'
 
 config.substitutions.append(('%{flags}', '--sysroot=@CMAKE_INSTALL_PREFIX@'))
 
diff --git a/lld/cmake/modules/AddLLD.cmake b/lld/cmake/modules/AddLLD.cmake
index 37f73afa915f..1f70cfe4fc05 100644
--- a/lld/cmake/modules/AddLLD.cmake
+++ b/lld/cmake/modules/AddLLD.cmake
@@ -17,8 +17,8 @@ macro(add_lld_library name)
     install(TARGETS ${name}
       COMPONENT ${name}
       ${export_to_lldtargets}
-      LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX}
-      ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX}
+      LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR}
+      ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR}
       RUNTIME DESTINATION "${CMAKE_INSTALL_BINDIR}")
 
     if (NOT CMAKE_CONFIGURATION_TYPES)
diff --git a/lldb/cmake/modules/AddLLDB.cmake b/lldb/cmake/modules/AddLLDB.cmake
index 6493df27f38d..e4fa0b72990e 100644
--- a/lldb/cmake/modules/AddLLDB.cmake
+++ b/lldb/cmake/modules/AddLLDB.cmake
@@ -106,7 +106,7 @@ function(add_lldb_library name)
   endif()
 
   if(PARAM_SHARED)
-    set(install_dest lib${LLVM_LIBDIR_SUFFIX})
+    set(install_dest ${CMAKE_INSTALL_LIBDIR})
     if(PARAM_INSTALL_PREFIX)
       set(install_dest ${PARAM_INSTALL_PREFIX})
     endif()
diff --git a/lldb/tools/intel-features/CMakeLists.txt b/lldb/tools/intel-features/CMakeLists.txt
index 7d48491ec89a..cb5f751a80ca 100644
--- a/lldb/tools/intel-features/CMakeLists.txt
+++ b/lldb/tools/intel-features/CMakeLists.txt
@@ -30,4 +30,4 @@ add_lldb_library(lldbIntelFeatures SHARED
   )
 
 install(TARGETS lldbIntelFeatures
-  LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX})
+  LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR})
diff --git a/llvm-spirv/LLVMSPIRVLib.pc.in b/llvm-spirv/LLVMSPIRVLib.pc.in
index 814c59251611..7188084e8061 100644
--- a/llvm-spirv/LLVMSPIRVLib.pc.in
+++ b/llvm-spirv/LLVMSPIRVLib.pc.in
@@ -1,7 +1,7 @@
 prefix=@CMAKE_INSTALL_PREFIX@
 exec_prefix=${prefix}
-libdir=${prefix}/lib@LLVM_LIBDIR_SUFFIX@
-includedir=${prefix}/include
+libdir=@CMAKE_INSTALL_FULL_LIBDIR@
+includedir=@CMAKE_INSTALL_FULL_INCLUDEDIR@
 
 Name: LLVMSPIRVLib
 Description: LLVM/SPIR-V bi-directional translator
diff --git a/llvm/CMakeLists.txt b/llvm/CMakeLists.txt
index 4518d3e1264d..ee11de0a3a09 100644
--- a/llvm/CMakeLists.txt
+++ b/llvm/CMakeLists.txt
@@ -1197,9 +1197,9 @@ if (NOT TENSORFLOW_AOT_PATH STREQUAL "")
   add_subdirectory(${TENSORFLOW_AOT_PATH}/xla_aot_runtime_src
     ${CMAKE_ARCHIVE_OUTPUT_DIRECTORY}/tf_runtime)
   install(TARGETS tf_xla_runtime EXPORT LLVMExports
-    ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT tf_xla_runtime)
+    ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT tf_xla_runtime)
   install(TARGETS tf_xla_runtime EXPORT LLVMDevelopmentExports
-    ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT tf_xla_runtime)
+    ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT tf_xla_runtime)
   set_property(GLOBAL APPEND PROPERTY LLVM_EXPORTS tf_xla_runtime)
   # Once we add more modules, we should handle this more automatically.
   if (DEFINED LLVM_OVERRIDE_MODEL_HEADER_INLINERSIZEMODEL)
diff --git a/llvm/cmake/modules/AddLLVM.cmake b/llvm/cmake/modules/AddLLVM.cmake
index d938214f9d0d..dc39a292aa90 100644
--- a/llvm/cmake/modules/AddLLVM.cmake
+++ b/llvm/cmake/modules/AddLLVM.cmake
@@ -955,8 +955,8 @@ macro(add_llvm_library name)
       endif()
       install(TARGETS ${name}
               ${export_to_llvmexports}
-              LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT ${name}
-              ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT ${name}
+              LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT ${name}
+              ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT ${name}
               RUNTIME DESTINATION "${CMAKE_INSTALL_BINDIR}" COMPONENT ${name})
 
       if (NOT LLVM_ENABLE_IDE)
@@ -2279,7 +2279,7 @@ function(llvm_install_library_symlink name dest type)
     set(LLVM_LINK_OR_COPY copy)
   endif()
 
-  set(output_dir lib${LLVM_LIBDIR_SUFFIX})
+  set(output_dir ${CMAKE_INSTALL_LIBDIR})
   if((WIN32 OR CYGWIN) AND "${type}" STREQUAL "SHARED")
     set(output_dir "${CMAKE_INSTALL_BINDIR}")
   endif()
@@ -2561,10 +2561,10 @@ function(llvm_setup_rpath name)
     # Since BUILD_SHARED_LIBS is only recommended for use by developers,
     # hardcode the rpath to build/install lib dir first in this mode.
     # FIXME: update this when there is better solution.
-    set(_install_rpath "${LLVM_LIBRARY_OUTPUT_INTDIR}" "${CMAKE_INSTALL_PREFIX}/lib${LLVM_LIBDIR_SUFFIX}" ${extra_libdir})
+    set(_install_rpath "${LLVM_LIBRARY_OUTPUT_INTDIR}" "${CMAKE_INSTALL_FULL_LIBDIR}" ${extra_libdir})
   elseif(UNIX)
-    set(_build_rpath "\$ORIGIN/../lib${LLVM_LIBDIR_SUFFIX}" ${extra_libdir})
-    set(_install_rpath "\$ORIGIN/../lib${LLVM_LIBDIR_SUFFIX}")
+    set(_build_rpath "${CMAKE_INSTALL_FULL_LIBDIR}" ${extra_libdir})
+    set(_install_rpath "${CMAKE_INSTALL_FULL_LIBDIR}")
     if("${CMAKE_SYSTEM_NAME}" MATCHES "(FreeBSD|DragonFly)")
       set_property(TARGET ${name} APPEND_STRING PROPERTY
                    LINK_FLAGS " -Wl,-z,origin ")
diff --git a/llvm/cmake/modules/AddOCaml.cmake b/llvm/cmake/modules/AddOCaml.cmake
index 9a393ae3b747..23b22a99ed74 100644
--- a/llvm/cmake/modules/AddOCaml.cmake
+++ b/llvm/cmake/modules/AddOCaml.cmake
@@ -150,9 +150,9 @@ function(add_ocaml_library name)
   endforeach()
 
   if( APPLE )
-    set(ocaml_rpath "@executable_path/../../../lib${LLVM_LIBDIR_SUFFIX}")
+    set(ocaml_rpath "@executable_path/../../../${CMAKE_INSTALL_LIBDIR}")
   elseif( UNIX )
-    set(ocaml_rpath "\\$ORIGIN/../../../lib${LLVM_LIBDIR_SUFFIX}")
+    set(ocaml_rpath "\\$ORIGIN/../../../${CMAKE_INSTALL_LIBDIR}")
   endif()
   list(APPEND ocaml_flags "-ldopt" "-Wl,-rpath,${ocaml_rpath}")
 
diff --git a/llvm/cmake/modules/CMakeLists.txt b/llvm/cmake/modules/CMakeLists.txt
index ef4cfa3acdb5..2ab47d564f76 100644
--- a/llvm/cmake/modules/CMakeLists.txt
+++ b/llvm/cmake/modules/CMakeLists.txt
@@ -130,7 +130,7 @@ set(LLVM_CONFIG_INCLUDE_DIRS
   )
 list(REMOVE_DUPLICATES LLVM_CONFIG_INCLUDE_DIRS)
 
-extend_path(LLVM_CONFIG_LIBRARY_DIR "\${LLVM_INSTALL_PREFIX}" "lib\${LLVM_LIBDIR_SUFFIX}")
+extend_path(LLVM_CONFIG_LIBRARY_DIR "\${LLVM_INSTALL_PREFIX}" "${CMAKE_INSTALL_LIBDIR}")
 set(LLVM_CONFIG_LIBRARY_DIRS
   "${LLVM_CONFIG_LIBRARY_DIR}"
   # FIXME: Should there be other entries here?
diff --git a/llvm/include/llvm/SYCLLowerIR/CMakeLists.txt b/llvm/include/llvm/SYCLLowerIR/CMakeLists.txt
index fee74421f102..99c7f2920a9b 100644
--- a/llvm/include/llvm/SYCLLowerIR/CMakeLists.txt
+++ b/llvm/include/llvm/SYCLLowerIR/CMakeLists.txt
@@ -8,5 +8,5 @@ tablegen(LLVM DeviceConfigFile.inc -gen-dynamic-tables)
 add_public_tablegen_target(DeviceConfigFile)
 install(FILES "${CMAKE_CURRENT_SOURCE_DIR}/DeviceConfigFile.hpp"
               "${CMAKE_CURRENT_BINARY_DIR}/DeviceConfigFile.inc"
-        DESTINATION include/llvm/SYCLLowerIR
+        DESTINATION ${CMAKE_INSTALL_INCLUDEDIR}/llvm/SYCLLowerIR
         COMPONENT DeviceConfigFile)
diff --git a/llvm/lib/ExecutionEngine/Interpreter/CMakeLists.txt b/llvm/lib/ExecutionEngine/Interpreter/CMakeLists.txt
index 8046bca2b1a4..997bd51e2b10 100644
--- a/llvm/lib/ExecutionEngine/Interpreter/CMakeLists.txt
+++ b/llvm/lib/ExecutionEngine/Interpreter/CMakeLists.txt
@@ -21,4 +21,4 @@ configure_file(
   Interpreter.h
   ${LLVM_BINARY_DIR}/include/llvm/ExecutionEngine/Interpreter/Interpreter.h)
 
-install(FILES Interpreter.h DESTINATION include/llvm/ExecutionEngine/Interpreter)
+install(FILES Interpreter.h DESTINATION ${CMAKE_INSTALL_INCLUDEDIR}/llvm/ExecutionEngine/Interpreter)
diff --git a/llvm/tools/llvm-config/BuildVariables.inc.in b/llvm/tools/llvm-config/BuildVariables.inc.in
index e4e1d449bf4d..890e1f164d97 100644
--- a/llvm/tools/llvm-config/BuildVariables.inc.in
+++ b/llvm/tools/llvm-config/BuildVariables.inc.in
@@ -23,6 +23,7 @@
 #define LLVM_CXXFLAGS "@LLVM_CXXFLAGS@"
 #define LLVM_BUILDMODE "@LLVM_BUILDMODE@"
 #define LLVM_LIBDIR_SUFFIX "@LLVM_LIBDIR_SUFFIX@"
+#define LLVM_INSTALL_FULL_LIBDIR "@CMAKE_INSTALL_FULL_LIBDIR@"
 #define LLVM_INSTALL_INCLUDEDIR "@CMAKE_INSTALL_INCLUDEDIR@"
 #define LLVM_INSTALL_PACKAGE_DIR "@LLVM_INSTALL_PACKAGE_DIR@"
 #define LLVM_TARGETS_BUILT "@LLVM_TARGETS_BUILT@"
diff --git a/llvm/tools/llvm-config/llvm-config.cpp b/llvm/tools/llvm-config/llvm-config.cpp
index 24ea264419af..26aaf93c4c71 100644
--- a/llvm/tools/llvm-config/llvm-config.cpp
+++ b/llvm/tools/llvm-config/llvm-config.cpp
@@ -367,7 +367,7 @@ int main(int argc, char **argv) {
       sys::path::make_absolute(ActivePrefix, Path);
       ActiveBinDir = std::string(Path);
     }
-    ActiveLibDir = ActivePrefix + "/lib" + LLVM_LIBDIR_SUFFIX;
+    ActiveLibDir = LLVM_INSTALL_FULL_LIBDIR;
     {
       SmallString<256> Path(LLVM_INSTALL_PACKAGE_DIR);
       sys::path::make_absolute(ActivePrefix, Path);
diff --git a/mlir/cmake/modules/AddMLIR.cmake b/mlir/cmake/modules/AddMLIR.cmake
index 6589458ab789..9bff1af30631 100644
--- a/mlir/cmake/modules/AddMLIR.cmake
+++ b/mlir/cmake/modules/AddMLIR.cmake
@@ -638,13 +638,13 @@ function(add_mlir_library_install name)
     install(TARGETS ${name}
       COMPONENT ${name}
       ${export_to_mlirtargets}
-      LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX}
-      ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX}
+      LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR}
+      ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR}
       RUNTIME DESTINATION "${CMAKE_INSTALL_BINDIR}"
       # Note that CMake will create a directory like:
       #   objects-${CMAKE_BUILD_TYPE}/obj.LibName
       # and put object files there.
-      OBJECTS DESTINATION lib${LLVM_LIBDIR_SUFFIX}
+      OBJECTS DESTINATION ${CMAKE_INSTALL_LIBDIR}
     )
 
     if (NOT LLVM_ENABLE_IDE)
diff --git a/mlir/cmake/modules/AddMLIRPython.cmake b/mlir/cmake/modules/AddMLIRPython.cmake
index 97873d0c07ab..1cdb8c4f9cc5 100644
--- a/mlir/cmake/modules/AddMLIRPython.cmake
+++ b/mlir/cmake/modules/AddMLIRPython.cmake
@@ -688,7 +688,7 @@ function(mlir_python_setup_extension_rpath target)
     set_property(TARGET ${target} APPEND PROPERTY
       BUILD_RPATH "${_real_lib_dir}")
     set_property(TARGET ${target} APPEND PROPERTY
-      INSTALL_RPATH "${_origin_prefix}/${ARG_RELATIVE_INSTALL_ROOT}/lib${LLVM_LIBDIR_SUFFIX}")
+      INSTALL_RPATH "${CMAKE_INSTALL_FULL_LIBDIR}")
   endif()
 endfunction()
 
diff --git a/offload/liboffload/CMakeLists.txt b/offload/liboffload/CMakeLists.txt
index 62480dad1cac..d6f0a0282c47 100644
--- a/offload/liboffload/CMakeLists.txt
+++ b/offload/liboffload/CMakeLists.txt
@@ -45,5 +45,5 @@ set_target_properties(LLVMOffload PROPERTIES
                       BUILD_RPATH "$ORIGIN:${CMAKE_CURRENT_BINARY_DIR}/..")
 install(TARGETS LLVMOffload LIBRARY COMPONENT LLVMOffload DESTINATION "${OFFLOAD_INSTALL_LIBDIR}")
 
-install(FILES ${CMAKE_CURRENT_BINARY_DIR}/API/OffloadAPI.h DESTINATION ${CMAKE_INSTALL_PREFIX}/include/offload)
-install(FILES ${CMAKE_CURRENT_BINARY_DIR}/API/OffloadPrint.hpp DESTINATION ${CMAKE_INSTALL_PREFIX}/include/offload)
+install(FILES ${CMAKE_CURRENT_BINARY_DIR}/API/OffloadAPI.h DESTINATION ${CMAKE_INSTALL_INCLUDEDIR}/offload)
+install(FILES ${CMAKE_CURRENT_BINARY_DIR}/API/OffloadPrint.hpp DESTINATION ${CMAKE_INSTALL_INCLUDEDIR}/offload)
diff --git a/openmp/libompd/gdb-plugin/CMakeLists.txt b/openmp/libompd/gdb-plugin/CMakeLists.txt
index 20cb4680e4cb..66a77274f9c8 100644
--- a/openmp/libompd/gdb-plugin/CMakeLists.txt
+++ b/openmp/libompd/gdb-plugin/CMakeLists.txt
@@ -36,5 +36,5 @@ target_link_libraries (ompdModule ${CMAKE_DL_LIBS})
 set_target_properties (ompdModule PROPERTIES PREFIX "")
 set_target_properties (ompdModule PROPERTIES LIBRARY_OUTPUT_DIRECTORY "${CMAKE_CURRENT_BINARY_DIR}/python-module/ompd/")
 
-install(DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}/python-module/ompd DESTINATION share/gdb/python/ PATTERN ompdModule.so PERMISSIONS OWNER_READ WORLD_READ GROUP_READ OWNER_EXECUTE GROUP_EXECUTE WORLD_EXECUTE)
+install(DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}/python-module/ompd DESTINATION ${CMAKE_INSTALL_DATAROOTDIR}/gdb/python/ PATTERN ompdModule.so PERMISSIONS OWNER_READ WORLD_READ GROUP_READ OWNER_EXECUTE GROUP_EXECUTE WORLD_EXECUTE)
 
diff --git a/polly/cmake/polly_macros.cmake b/polly/cmake/polly_macros.cmake
index 9bd7b0b0ea59..1232f5f0d748 100644
--- a/polly/cmake/polly_macros.cmake
+++ b/polly/cmake/polly_macros.cmake
@@ -46,8 +46,8 @@ macro(add_polly_library name)
     install(TARGETS ${name}
       COMPONENT ${name}
       ${exports}
-      LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX}
-      ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX})
+      LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR}
+      ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR})
     add_llvm_install_targets(install-${name}
       COMPONENT ${name})
   endif()
diff --git a/sycl/CMakeLists.txt b/sycl/CMakeLists.txt
index 9d11782674dd..2969893f4b4a 100644
--- a/sycl/CMakeLists.txt
+++ b/sycl/CMakeLists.txt
@@ -295,7 +295,7 @@ add_custom_command(
 install(DIRECTORY "${sycl_inc_dir}/sycl" DESTINATION ${SYCL_INCLUDE_DIR} COMPONENT sycl-headers)
 install(DIRECTORY "${sycl_inc_dir}/CL" DESTINATION ${SYCL_INCLUDE_DIR}/ COMPONENT sycl-headers)
 install(DIRECTORY "${sycl_inc_dir}/std" DESTINATION ${SYCL_INCLUDE_DIR} COMPONENT sycl-headers)
-install(DIRECTORY "${UNIFIED_RUNTIME_INCLUDE_DIR}/unified-runtime" DESTINATION ${SYCL_INCLUDE_DIR} COMPONENT sycl-headers)
+install(DIRECTORY "${UNIFIED_RUNTIME_INCLUDE_DIR}/unified-runtime" DESTINATION ${CMAKE_INSTALL_INCLUDEDIR} COMPONENT sycl-headers)
 
 if (WIN32)
   set(SYCL_RT_LIBS sycl${SYCL_MAJOR_VERSION})
@@ -348,13 +348,13 @@ if (NOT WIN32)
   install(FILES
     "${CMAKE_CURRENT_SOURCE_DIR}/gdb/libsycl.so-gdb.py"
     RENAME "libsycl.so.${SYCL_VERSION_STRING}-gdb.py"
-    DESTINATION "lib${LLVM_LIBDIR_SUFFIX}/"
+    DESTINATION ${CMAKE_INSTALL_LIBDIR}/
     COMPONENT sycl-headers-extras)
   if (SYCL_ENABLE_MAJOR_RELEASE_PREVIEW_LIB)
     install(FILES
       "${CMAKE_CURRENT_SOURCE_DIR}/gdb/libsycl.so-gdb.py"
       RENAME "libsycl-preview.so.${SYCL_VERSION_STRING}-gdb.py"
-      DESTINATION "lib${LLVM_LIBDIR_SUFFIX}/"
+      DESTINATION ${CMAKE_INSTALL_LIBDIR}/
       COMPONENT sycl-headers-extras)
   endif()
 
diff --git a/sycl/cmake/modules/BuildUnifiedRuntime.cmake b/sycl/cmake/modules/BuildUnifiedRuntime.cmake
index 646ca364a10f..724569d6c9fe 100644
--- a/sycl/cmake/modules/BuildUnifiedRuntime.cmake
+++ b/sycl/cmake/modules/BuildUnifiedRuntime.cmake
@@ -112,9 +112,9 @@ find_package(Threads REQUIRED)
 if(TARGET UnifiedRuntimeLoader)
   # Install the UR loader.
   install(TARGETS ur_loader
-    LIBRARY DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT unified-runtime-loader
-    ARCHIVE DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT unified-runtime-loader
-    RUNTIME DESTINATION "bin" COMPONENT unified-runtime-loader
+    LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT unified-runtime-loader
+    ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT unified-runtime-loader
+    RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT unified-runtime-loader
   )
 endif()
 
@@ -124,8 +124,8 @@ function(add_sycl_ur_adapter NAME)
   add_dependencies(UnifiedRuntimeAdapters ur_adapter_${NAME})
 
   install(TARGETS ur_adapter_${NAME}
-    LIBRARY DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT ur_adapter_${NAME}
-    RUNTIME DESTINATION "bin" COMPONENT ur_adapter_${NAME})
+    LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT ur_adapter_${NAME}
+    RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT ur_adapter_${NAME})
 
   set(manifest_file
     ${CMAKE_CURRENT_BINARY_DIR}/install_manifest_ur_adapter_${NAME}.txt)
@@ -278,24 +278,24 @@ if(CMAKE_SYSTEM_NAME STREQUAL Windows)
   # Add the debug UR runtime libraries to the parent install.
   install(
     FILES ${URD_INSTALL_DIR}/bin/ur_loaderd.dll
-    DESTINATION "bin" COMPONENT unified-runtime-loader)
+    DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT unified-runtime-loader)
   foreach(adapter ${SYCL_ENABLE_BACKENDS})
     install(
       FILES ${URD_INSTALL_DIR}/bin/ur_adapter_${adapter}d.dll
-      DESTINATION "bin" COMPONENT ur_adapter_${adapter})
+      DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT ur_adapter_${adapter})
     add_dependencies(install-sycl-ur-adapter-${adapter} unified-runtimed)
   endforeach()
   if(UMF_BUILD_SHARED_LIBRARY)
     # Also install umfd.dll
     install(
       FILES ${URD_INSTALL_DIR}/bin/umfd.dll
-      DESTINATION "bin" COMPONENT unified-memory-framework)
+      DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT unified-memory-framework)
   endif()
 endif()
 
 if(TARGET umf)
   install(TARGETS umf
-    LIBRARY DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT unified-memory-framework
-    ARCHIVE DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT unified-memory-framework
-    RUNTIME DESTINATION "bin" COMPONENT unified-memory-framework)
+    LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT unified-memory-framework
+    ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT unified-memory-framework
+    RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT unified-memory-framework)
 endif()
diff --git a/sycl/cmake/modules/SYCLUtils.cmake b/sycl/cmake/modules/SYCLUtils.cmake
index f469b2604760..a8728bdfb5b1 100644
--- a/sycl/cmake/modules/SYCLUtils.cmake
+++ b/sycl/cmake/modules/SYCLUtils.cmake
@@ -13,7 +13,7 @@ macro(add_stripped_pdb ARG_TARGET_NAME)
     target_link_options(${ARG_TARGET_NAME}
                         PRIVATE "LINKER:/PDBSTRIPPED:${ARG_TARGET_NAME}.stripped.pdb")
     install(FILES "${CMAKE_CURRENT_BINARY_DIR}/${ARG_TARGET_NAME}.stripped.pdb"
-            DESTINATION ${CMAKE_INSTALL_PREFIX}/bin
+            DESTINATION ${CMAKE_INSTALL_BINDIR}
             RENAME "${ARG_TARGET_NAME}.pdb"
             COMPONENT ${ARG_TARGET_NAME}
             OPTIONAL)
diff --git a/sycl/source/CMakeLists.txt b/sycl/source/CMakeLists.txt
index 40327b594678..5f25cb498381 100644
--- a/sycl/source/CMakeLists.txt
+++ b/sycl/source/CMakeLists.txt
@@ -198,7 +198,7 @@ function(add_sycl_rt_library LIB_NAME LIB_OBJ_NAME)
         COMMENT "Creating version-agnostic copy of the import library.")
       install(
         FILES ${CMAKE_LIBRARY_OUTPUT_DIRECTORY}/${ARG_IMPLIB_NAME}.lib
-        DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT sycl)
+        DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT sycl)
     endif()
   endif()
 
@@ -436,6 +436,6 @@ if (WIN32)
 endif()
 
 install(TARGETS ${SYCL_RT_LIBS}
-  ARCHIVE DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT sycl
-  LIBRARY DESTINATION "lib${LLVM_LIBDIR_SUFFIX}" COMPONENT sycl
-  RUNTIME DESTINATION "bin" COMPONENT sycl)
+  ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT sycl
+  LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT sycl
+  RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT sycl)
diff --git a/sycl/test/CMakeLists.txt b/sycl/test/CMakeLists.txt
index 4e7607e74931..d400c6b11d89 100644
--- a/sycl/test/CMakeLists.txt
+++ b/sycl/test/CMakeLists.txt
@@ -8,7 +8,7 @@ set(LLVM_BUILD_BINARY_DIRS "${LLVM_BINARY_DIR}/bin/")
 set(LLVM_BUILD_LIBRARY_DIRS "${LLVM_BINARY_DIR}/lib/")
 
 set(RT_TEST_ARGS ${RT_TEST_ARGS} "-v")
-set(DEPLOY_RT_TEST_ARGS ${DEPLOY_RT_TEST_ARGS} "-v -D SYCL_TOOLS_DIR=${CMAKE_INSTALL_PREFIX}/bin -D SYCL_LIBS_DIR=${CMAKE_INSTALL_PREFIX}/lib${LLVM_LIBDIR_SUFFIX} -D SYCL_INCLUDE=${CMAKE_INSTALL_PREFIX}/${SYCL_INCLUDE_DIR}")
+set(DEPLOY_RT_TEST_ARGS ${DEPLOY_RT_TEST_ARGS} "-v -D SYCL_TOOLS_DIR=${CMAKE_INSTALL_FULL_BINDIR} -D SYCL_LIBS_DIR=${CMAKE_INSTALL_FULL_LIBDIR} -D SYCL_INCLUDE=${CMAKE_INSTALL_PREFIX}/${SYCL_INCLUDE_DIR}")
 
 find_package(Threads REQUIRED)
 set(SYCL_THREADS_LIB ${CMAKE_THREAD_LIBS_INIT})
diff --git a/sycl/tools/sycl-ls/CMakeLists.txt b/sycl/tools/sycl-ls/CMakeLists.txt
index a1cb33c6553b..7d93fbb79144 100644
--- a/sycl/tools/sycl-ls/CMakeLists.txt
+++ b/sycl/tools/sycl-ls/CMakeLists.txt
@@ -26,4 +26,4 @@ if (WIN32)
   target_link_options(sycl-ls PRIVATE LINKER:/DEPENDENTLOADFLAG:0x900)
 endif()
 install(TARGETS sycl-ls
-  RUNTIME DESTINATION "bin" COMPONENT sycl-ls)
+  RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT sycl-ls)
diff --git a/sycl/tools/syclbin-dump/CMakeLists.txt b/sycl/tools/syclbin-dump/CMakeLists.txt
index d1eb71823f64..9bf370bdcbe4 100644
--- a/sycl/tools/syclbin-dump/CMakeLists.txt
+++ b/sycl/tools/syclbin-dump/CMakeLists.txt
@@ -22,4 +22,4 @@ endif()
 add_dependencies(sycl-toolchain syclbin-dump)
 
 install(TARGETS syclbin-dump
-  RUNTIME DESTINATION "bin" COMPONENT syclbin-dump)
+  RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT syclbin-dump)
diff --git a/sycl/ur_win_proxy_loader/CMakeLists.txt b/sycl/ur_win_proxy_loader/CMakeLists.txt
index 740a764269ea..dc8b98f83098 100644
--- a/sycl/ur_win_proxy_loader/CMakeLists.txt
+++ b/sycl/ur_win_proxy_loader/CMakeLists.txt
@@ -14,7 +14,7 @@ configure_file(../../llvm/resources/windows_version_resource.rc ${CMAKE_CURRENT_
 add_library(ur_win_proxy_loader SHARED  ur_win_proxy_loader.cpp  ${CMAKE_CURRENT_BINARY_DIR}/versioninfo.rc)
 add_dependencies(ur_win_proxy_loader UnifiedRuntimeLoader)
 install(TARGETS ur_win_proxy_loader
-  RUNTIME DESTINATION "bin" COMPONENT ur_win_proxy_loader
+  RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT ur_win_proxy_loader
 )
 
 if (MSVC)
@@ -65,5 +65,5 @@ if (MSVC)
   target_link_options(ur_win_proxy_loaderd PRIVATE LINKER:/DEPENDENTLOADFLAG:0x2000)
   target_link_options(ur_win_proxy_loader PRIVATE LINKER:/DEPENDENTLOADFLAG:0x2000)
   install(TARGETS ur_win_proxy_loaderd
-    RUNTIME DESTINATION "bin" COMPONENT ur_win_proxy_loader)
+    RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT ur_win_proxy_loader)
 endif()
diff --git a/unified-runtime/CMakeLists.txt b/unified-runtime/CMakeLists.txt
index 2248cfcb3db2..b6c102721858 100644
--- a/unified-runtime/CMakeLists.txt
+++ b/unified-runtime/CMakeLists.txt
@@ -363,7 +363,7 @@ target_include_directories(ur_headers INTERFACE
 # Add the include directory and the headers target to the install.
 install(
     DIRECTORY "${PROJECT_SOURCE_DIR}/include/"
-    DESTINATION include COMPONENT ur_headers)
+    DESTINATION ${CMAKE_INSTALL_INCLUDEDIR} COMPONENT ur_headers)
 install(
     TARGETS ur_headers
     EXPORT ${PROJECT_NAME}-targets)
@@ -386,7 +386,7 @@ install(
     EXPORT ${PROJECT_NAME}-targets
     FILE ${PROJECT_NAME}-targets.cmake
     NAMESPACE ${PROJECT_NAME}::
-    DESTINATION lib/cmake/${PROJECT_NAME})
+    DESTINATION ${CMAKE_INSTALL_LIBDIR}/cmake/${PROJECT_NAME})
 
 # Configure the package versions file for use in find_package when installed.
 write_basic_package_version_file(
@@ -397,14 +397,14 @@ write_basic_package_version_file(
 configure_package_config_file(
     ${PROJECT_SOURCE_DIR}/cmake/${PROJECT_NAME}-config.cmake.in
     ${PROJECT_BINARY_DIR}/cmake/${PROJECT_NAME}-config.cmake
-    INSTALL_DESTINATION lib/cmake/${PROJECT_NAME})
+    INSTALL_DESTINATION ${CMAKE_INSTALL_LIBDIR}/cmake/${PROJECT_NAME})
 
 # Add the package files to the install.
 install(
     FILES
         ${PROJECT_BINARY_DIR}/cmake/${PROJECT_NAME}-config.cmake
         ${PROJECT_BINARY_DIR}/cmake/${PROJECT_NAME}-config-version.cmake
-    DESTINATION lib/cmake/${PROJECT_NAME})
+    DESTINATION ${CMAKE_INSTALL_LIBDIR}/cmake/${PROJECT_NAME})
 
 set(API_JSON_FILE ${PROJECT_BINARY_DIR}/unified_runtime.json)
 
diff --git a/unified-runtime/source/loader/libur_loader.pc.in b/unified-runtime/source/loader/libur_loader.pc.in
index d79c3a9da8bd..6aac2abcd9ea 100644
--- a/unified-runtime/source/loader/libur_loader.pc.in
+++ b/unified-runtime/source/loader/libur_loader.pc.in
@@ -1,6 +1,6 @@
 prefix=@CMAKE_INSTALL_PREFIX@
-includedir=${prefix}/include
-libdir=${prefix}/lib
+includedir=@CMAKE_INSTALL_FULL_INCLUDEDIR@
+libdir=@CMAKE_INSTALL_FULL_LIBDIR@
 
 
 Name: Unified Runtime Loader
diff --git a/xpti/src/CMakeLists.txt b/xpti/src/CMakeLists.txt
index 0f6692c18347..5728d1834f8a 100644
--- a/xpti/src/CMakeLists.txt
+++ b/xpti/src/CMakeLists.txt
@@ -22,9 +22,9 @@ macro(add_xpti_lib target_name)
   # Set the location of the library installation.
   install(TARGETS ${target_name}
     EXPORT xptiTargets
-    RUNTIME DESTINATION bin COMPONENT xpti
-    LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT xpti
-    ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT xpti
+    RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT xpti
+    LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT xpti
+    ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT xpti
   )
 endmacro()
 
diff --git a/xptifw/CMakeLists.txt b/xptifw/CMakeLists.txt
index 78549309cafe..29d29e005b1b 100644
--- a/xptifw/CMakeLists.txt
+++ b/xptifw/CMakeLists.txt
@@ -13,9 +13,9 @@ set(SAMPLES_DIR ${CMAKE_CURRENT_LIST_DIR}/samples)
 if (NOT DEFINED XPTI_DIR) # don't overwrite if already set
   if (NOT DEFINED XPTI_SOURCE_DIR)
     # If XPTI_SOURCE_DIR is not provided then assume that xpti is in-tree and not external.
-    set(XPTI_DIR ${CMAKE_CURRENT_LIST_DIR}/../xpti)
+    get_filename_component(XPTI_DIR ${CMAKE_CURRENT_LIST_DIR}/../xpti ABSOLUTE)
   else()
-    set(XPTI_DIR ${XPTI_SOURCE_DIR}/../xpti)
+    get_filename_component(XPTI_DIR ${XPTI_SOURCE_DIR}/../xpti ABSOLUTE)
   endif()
 endif()
 
diff --git a/xptifw/src/CMakeLists.txt b/xptifw/src/CMakeLists.txt
index 5e865aa3714e..10e6bfc925e3 100644
--- a/xptifw/src/CMakeLists.txt
+++ b/xptifw/src/CMakeLists.txt
@@ -93,9 +93,9 @@ function(add_xpti_library LIB_NAME)
   include(GNUInstallDirs)
   install(TARGETS ${LIB_NAME}
     EXPORT xptifwTargets
-    RUNTIME DESTINATION bin COMPONENT xptifw
-    LIBRARY DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT xptifw
-    ARCHIVE DESTINATION lib${LLVM_LIBDIR_SUFFIX} COMPONENT xptifw
+    RUNTIME DESTINATION ${CMAKE_INSTALL_BINDIR} COMPONENT xptifw
+    LIBRARY DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT xptifw
+    ARCHIVE DESTINATION ${CMAKE_INSTALL_LIBDIR} COMPONENT xptifw
   )
 endfunction(add_xpti_library)